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OCR: w in l'estosterone concentrations are quite lo after the prepubertal boys but consistently increas on in early onset of enhanced gonadotrophin secret during puberty, with exponential rises occurring stages 2 and 3 of pubertal development. s secreted The major female oestrogen, oestradiol, nount mainly by the ovary, although a small a arises from extraglandular conversion o adiol testosterone and androstenedione. Oestr nd then increases during pubertal development menstrualvaries in association with the stage of th cycle,